{{Infobox royalty|consort=yes|father=[[Manuel I,. King of PortugalPortugalski]]|religion=[[Roman Catholicism]]|burial_place=[[El Escorial]]|death_place=[[Toledo, Spain|Toledo]], Spain|death_date={{death date and age|1539|5|1|1503|10|24|df=y}}|birth_place=[[Lisbon]], Portugal|birth_date=24 October 1503|mother=[[Maria of Aragon, Queen of Portugal|Maria of Aragon]]|house=[[House of Aviz|Aviz]]|image=La emperatriz Isabel de Portugal, por Tiziano.jpg|issue={{plainlist|
* [[PhilipFilip II,. King of SpainŠpanski]]
* [[Marija Habsburška]]
* [[Maria of Spain|Maria, Holy Roman Empress]]
* [[Ivana Habsburška]]
* [[Joanna of Austria, Princess of Portugal|Joanna, Princess of Portugal]]
}}|spouse={{marriage|[[Karel V. Habsburški]]|1526}}|reign1=10 March 1526 – 1 May 1539|succession1={{plainlist|
