MERS-CoV: Razlika med redakcijama

|author=De Groot RJ |title=Middle East Respiratory Syndrome Coronavirus (MERS-CoV): Announcement of the Coronavirus Study Group |journal=Journal of Virology |date=15 May 2013 | doi=10.1128/JVI.01244-13 |pmid=23678167 |pmc=3700179 |volume=87 |issue=14 |pages=7790–2|author-separator= |author2display-authors=and others |displayauthors=1 etal}}</ref> Imenovan tudi '''Kamelja gripa'''<ref> {{cite web|url=http://www.thetimes.co.uk/tto/news/world/asia/article4465150.ece|title=Travel alert after eighth camel flu death}}</ref> ali ''<nowiki/>'EMC / 2012'<nowiki/>'' ([[HCoV-EMC / 2012]]), je nova vrsta v rodu [[Beta koronavirus]]ov, z enovijačno RNA pozitivne smeri.

[[Egipt|Egipčanski]] virolog Dr. Ali Mohamed Zaki je iz moških [[človeška pljuča |pljuč]] izoliral in identificiral dotlej neznan koronavirus.<ref name="zaki8nov2012">{{cite journal |authorauthor1=Ali Mohamed Zaki |author2=Sander van Boheemen |author3=Theo M. Bestebroer |author4=Albert D.M.E. Osterhaus |author5=Ron A.M. Fouchier |title=Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia |journal=New England Journal of Medicine |volume=367 |date=8 November 2012 |pages=1814–20 |url=http://www.virology-bonn.de/fileadmin/user_upload/_temp_/Zaki_et_al.pdf |format=PDF |doi=10.1056/NEJMoa1211721|issue=19 |pmid=23075143}}</ref> <ref name="thechart.blogs">{{cite news |last=Falco |first=Miriam |title=New SARS-like virus poses medical mystery |url= http://thechart.blogs.cnn.com/2012/09/24/new-sars-like-virus-poses-medical-mystery/ |accessdate=27 September 2012 |publisher=CNN |date=24 September 2012}}</ref> <ref>{{cite news |last=Dziadosz |first=Alexander |title=The doctor who discovered a new SARS-like virus says it will probably trigger an epidemic at some point, but not necessarily in its current form.

|url=http://www.reuters.com/article/2013/05/13/us-coronavirus-egypt-idUSBRE94C0MH20130513 |accessdate=25 May 2013 |newspaper=Reuters |date=13 May 2013}}</ref> Dr. Zaki je nato svoje ugotovitve 24. septembra 2012 objavil na [[Promed-mail]].<ref name="thechart.blogs" /> <ref name="promedmail.org"/> <ref name="promedmail.org">{{cite web |title=See Also |publisher=[[ProMED-mail]] |date=2012-09-20 |url=http://www.promedmail.org/direct.php?id=20120920.1302733 |accessdate=2013-05-31}}</ref> Izolirane celice so izkazovale [[citopatski efekt|citopatske vplive]] (CPE), vidne kot zaokroževanje celic in nastanek [[Sincitium |sincicij]].<ref name="promedmail.org"/>

{{Cite journal|last1=Kindler|first1=E.|last2=Jónsdóttir|first2=H. R.|last3=Muth|first3=D.|last4=Hamming|first4=O. J.|last5=Hartmann|first5=R.|last6=Rodriguez|first6=R.|last7=Geffers|first7=R.|last8=Fouchier|first8=R. A.|last9=Drosten|first9=C.|title=Efficient Replication of the Novel Human Betacoronavirus EMC on Primary Human Epithelium Highlights Its Zoonotic Potential|journal=MBio|volume=4|issue=1|pages=e00611–12|year=2013|doi= 10.1128/mBio.00611-12|pmid=23422412|pmc=3573664|displayauthors=3}}</ref> <ref name="Raj-2013">{{Cite journal|last1=Raj|first1=V. S.|last2=Mou|first2=H.|last3=Smits|first3=S. L.|last4=Dekkers|first4=D. H.|last5=Müller|first5=M. A.|last6=Dijkman|first6=R.|last7=Muth|first7=D.|last8=Demmers|first8=J. A.|last9=Zaki|first9 = A.|title=Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC|journal=Nature|volume=495|issue=7440|pages=251–4|date=March 2013|doi=10.1038/nature12005|pmid=23486063|displayauthors=3}}</ref>

13. Februarja 2013 je SZO opozorila, da "virus MERS-CoV predstavlja grožnjo za ves svet."<ref>{{cite news|title=WHO calls Middle Eastern virus, MERS, 'threat to the entire world' as death toll rises to 27|url=http://www.dailymail.co.uk/news/article-2332677/WHO-calls-Middle-Eastern-virus-MERS-threat-entire-world-death-toll-rises-27.html?ito=feeds-newsxml|accessdate=29 May 2013 |newspaper=Daily Mail|date=29 May 2013}}</ref> Vendar pa je Dr. [[Anthony S. Fauci]], sodelavec [[National Institutes of Health|NIH]] v Bethesdi, Maryland, bil mnenja, da se MERS-CoV za zdaj "sploh ne širi trajno od človeka do človeka." Po Dr. Fauciju pa nevarnost, da virus mutira v seve, ki se prenašajo od osebe do osebe, obstaja.<ref>{{cite web|url=http://www.washingtontimes.com/video/national-news/fauci-new-virus-not-yet-a-threat-to-the-world/ |title=Fauci: New Virus Not Yet a 'threat to the world' (video) |publisher=Washington Times |date=2012-08-31 |accessdate=2013-05-31}}</ref>

Dr Zakiju, ki je kot prvi izoliral človeški sev, savdski uradniki niso dovolili, da lahko vzorec virusa pošlje Fouchieru; razjezilo jih je, da je Fouchier vložil zahtevo za patent na celotno gensko sekvenco<ref name=Economist20apr2013>

Urednik ''[[Economist]]a'' je pripomnil: "Zaskrbljenost zaradi varnosti ne sme upočasniti nujnih del. Raziskovati smrtonosni virus je tvegano. Ne ga raziskovati pa je še bolj tvegano.<ref name=Economist20apr2013/> Dr. Zakija so zato, ker je delil svoje vzorce in spoznanja, dali odpoved.<ref>{{cite news|title=Egyptian Virologist Who Discovered New SARS-Like Virus Fears Its Spread|url=http://health.mpelembe.net/home/egyptian-virologist-who-discovered-new-sars-like-virus-fears-its-spread|accessdate=25 May 2013|newspaper=Mpelembe|date=13 May 2013}}</ref> <ref>{{cite news|title=Coronavirus victim's widow tells of grief as scientists scramble for treatment|url=http://www.guardian.co.uk/science/2013/mar/15/coronavirus-victim-widow-scientists-treatment|accessdate=25 May 2013|newspaper=[[The Guardian]]|date=15 March 2013|author=Ian Sample|author2=Mark Smith}}</ref> <ref>{{cite news|last=Sample|first=Ian|title=Coronavirus: Is this the next pandemic?|url=http://www.guardian.co.uk/science/2013/mar/15/coronavirus-next-global-pandemic|accessdate=25 May 2013|newspaper=The Guardian|date=15 March 2013}}</ref> <ref>{{cite news|last=Yang|first=Jennifer|title=How medical sleuths stopped a deadly new SARS-like virus in its tracks|url=http://www.thestar.com/news/world/2012/10/21/how_medical_sleuths_stopped_a_deadly_new_sarslike_virus_in_its_tracks.html|accessdate=25 May 2013|newspaper=[[Toronto Star]]|date=21 October 2012}}</ref>