CD4: Razlika med redakcijama

dodanih 92 zlogov ,  pred 3 leti
m
pp
m (Bot: Popravljanje preusmeritev)
m (pp)
[[Slika:PDB 1wip EBI.jpg|right|thumb|350px|Struktura glikoproteina cd4 na površini limfocitov T]]
 
'''CD4''' ('''[[označevalec pripadnosti]] 4''') je [[glikoprotein]], ki ga na svoji površini izražajo [[celica pomagalka|celice pomagalke]], [[monocit]]i, [[makrofag]]i in [[dendritična celica|dendritične celice]]. Odkrili so ga konec 70-ih let prejšnjega stoletja in so ga sprva poimenovali leu-3 in T4, ime CD4 pa je bilo določeno leta 1984.<ref name="isbn0-387-12056-4">{{cite book | author = Alain Bernard | authorlink = | editor = | others = | title = Leucocyte typing: human leucocyte differentiation antigens detected by monoclonal antibodies: specification, classification, nomenclature: [report on the first international references workshop sponsored by INSERM, WHO and IUIS] | edition = | language = | publisher = Springer | location = Berlin | year = 1984 | origyear = | pages = pages 45–48 | quote = | isbn = 0-387-12056-4 | oclc = | doi = | url = | accessdate = }}</ref> Pri ljudeh nosi zapis za beljakovino CD4 [[gen]] ''CD4''.<ref name="pmid3086883">{{cite journal | authorauthor1 = Isobe M,|author2= Huebner K,|author3= Maddon PJ,|author4= Littman DR,|author5= Axel R,|author6= Croce CM | title = The gene encoding the T-cell surface protein T4 is located on human chromosome 12 | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 83 | issue = 12 | pages = 4399–4402 | year = junij 1986 | month = June | pmid = 3086883 | pmc = 323740 | doi = 10.1073/pnas.83.12.4399| url = http://www.pnas.org/cgi/pmidlookup?view=long&pmid=3086883 | issn = }}</ref><ref name="pmid8723724">{{cite journal | authorauthor1 = Ansari-Lari MA,|author2= Muzny DM,|author3= Lu J,|author4= Lu F,|author5= Lilley CE,|author6= Spanos S,|author7= Malley T,|author8= Gibbs RA | title = A gene-rich cluster between the CD4 and triosephosphate isomerase genes at human chromosome 12p13 | journal = Genome Res. | volume = 6 | issue = 4 | pages = 314–26 | year =april 1996 | month = April | pmid = 8723724 | doi = 10.1101/gr.6.4.314| url = http://www.genome.org/cgi/pmidlookup?view=long&pmid=8723724 | issn = }}</ref>
 
== Zgradba ==
57.312

urejanj