Histidin: Razlika med redakcijama

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Infopolje
(Nova stran z vsebino: '''Histidin''' (okrajšano kot '''His''' ali '''H''')<ref> IUPAC-IUBMB Joint Commission on Biochemical Nomenclature. [http://www.chem.qmul.ac.uk/iupac/AminoAcid/ ''Nomencla...)
 
(Infopolje)
{{chembox
| verifiedrevid = 443858318
| Name = <small>L</small>-Histidin
| ImageFileL1_Ref = {{chemboximage|correct|??}}
| ImageFileL1 = Histidin - Histidine.svg
| ImageFileR1 = L-histidine-zwitterion-from-xtal-1993-3D-balls-B.png
| IUPACName = Histidin
| OtherNames = 2-amino-3-(1''H''-imidazol-4-il)propanojska kislina
| Section1 = {{Chembox Identifiers
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 6038
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 4QD397987E
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D00032
| InChI = 1/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1
| InChIKey = HNDVDQJCIGZPNO-YFKPBYRVBM
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 17962
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = HNDVDQJCIGZPNO-YFKPBYRVSA-N
| CASNo = 71-00-1
| CASNo_Ref = {{cascite|correct|CAS}}
| PubChem = 773
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank = DB00117
| ChEBI_Ref = {{ebicite|correct|EBI}}
| ChEBI = 57595
| SMILES = O=C(O)[C@@H](N)Cc1cncn1
}}
| Section2 = {{Chembox Properties
| C=6 | H=9 | N=3 | O=2
| Appearance =
| Density =
| MeltingPt =
| BoilingPt =
| Solubility = 4,19g/100g pri 25&nbsp;°C <ref>http://prowl.rockefeller.edu/aainfo/solub.htm</ref>
}}
| Section3 = {{Chembox Hazards
| NFPA-H = 1
| NFPA-F = 1
| NFPA-R = 0
| MainHazards =
| FlashPt =
| Autoignition = }}
}}
'''Histidin''' (okrajšano kot '''His''' ali '''H''')<ref> IUPAC-IUBMB Joint Commission on Biochemical Nomenclature. [http://www.chem.qmul.ac.uk/iupac/AminoAcid/ ''Nomenclature and Symbolism for Amino Acids and Peptides''].Recommendations on Organic & Biochemical Nomenclature, Symbols & Terminology etc. Pridobljeno 17. maja 2007.</ref> je α-[[aminokislina]] z [[imidazol]]no funkcionalno skupino. Je ena od 23 proteinogenih aminokislin. Njena [[genetski kod#DNK kodoni|kodona]] sta CAU in CAC. Prvi jo je izoliral nemški zdravnik Albrecht Kossel leta 1896. Spada med človekove in živalske esencialne aminokisline, čeprav se je na začetku domnevalo, da to velja samo za dojenčke.<ref>J.D. Kopple,M.E. Swendseid (1975). [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC301830/ ''Evidence that histidine is an essential amino acid in normal and chronically uremic man'']. Journal of Clinical Investigation '''55''' (5): 881–891. doi: 10.1172/JCI108016. PMC 301830. PMID 1123426.</ref>
 
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